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Cholesterol

The extensive range of generic products marketed by Novagen Pharma (Pty) Ltd conform to strict international standards.
Further information is available on request. For full prescribing information refer to the approved Professional Information Leaflet.

Registration Number Trade Name Active Ingredient/Strength Dosage Form Schedule Pack size PIL
41/7.5/0382 Novatin® 10 Simvastatin 10 mg Tabs S4 30
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41/7.5/0383 Novatin® 20 Simvastatin 20 mg Tabs S4 30
  • Patient Information Leaflet
    Adobe PDF, 206 KB
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41/7.5/0384 Novatin® 40 Simvastatin 40 mg Tabs S4 30
  • Patient Information Leaflet
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More about: Cholesterol

Serum cholesterol reducers act together with diet, weight-loss and exercise to reduce the risk of heart attack and stroke.

Hypercholesterolemia is a condition characterized by very high levels of cholesterol in the blood. Cholesterol is a waxy, fat-like substance that is produced in the body and obtained from foods that come from animals (particularly egg yolks, meat, poultry, fish, and dairy products). The body needs this substance to build cell membranes, make certain hormones, and produce compounds that aid in fat digestion. Too much cholesterol, however, increases a person's risk of developing heart disease. 1

People with hypercholesterolemia have a high risk of developing a form of heart disease called coronary artery disease. This condition occurs when excess cholesterol in the bloodstream is deposited in the walls of blood vessels, particularly in the arteries that supply blood to the heart (coronary arteries). The abnormal build-up of cholesterol forms clumps (plaque) that narrow and harden artery walls. As the clumps get bigger, they can clog the arteries and restrict the flow of blood to the heart. The build-up of plaque in coronary arteries causes a form of chest pain called angina and greatly increases a person's risk of having a heart attack. 1

Inherited forms of hypercholesterolemia can also cause health problems related to the build-up of excess cholesterol in other tissues. If cholesterol accumulates in tendons, it causes characteristic growths called tendon xanthomas. These growths most often affect the Achilles tendons and tendons in the hands and fingers. Yellowish cholesterol deposits under the skin of the eyelids are known as xanthelasmata. Cholesterol can also accumulate at the edges of the clear, front surface of the eye (the cornea), leading to a gray-colored ring called an arcus cornealis. 1

Reference:

  1. https://ghr.nlm.nih.gov/condition/hypercholesterolemia

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